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T M C » P U L S E | N O V E M B E R 2 0 1 8 23 Buy, build, refinance — let Amegy Bank ® help Amegy Bank offers many unique private banking mortgage programs tailored specifically for physicians. · Special mortgage program for new physicians with low down payments and competitive interest rates. · One-Time Close construction and permanent mortgage program which saves you time and money when you are ready to build your dream home. Give us a call to find out how we can help you create home financing that meets your particular needs. Amegy Bank. Here, you grow. *Loans subject to credit approval. Terms and conditions apply, see mortgage banker for details. A division of ZB, N.A. Member FDIC, NMLS# 467014 Equal Housing Lender © 2018 ZB, N.A. Jordan Golson Vice President, Private Banking 815 Walker Street, Suite 1350 Houston, TX 77002 NMLS# 1094641 713.235.8825 | jordan.golson@amegybank.com when they pulled up in a rented Ford Mustang convertible, the valets assumed they were with the band and escorted them into the affair. "It was an open bar, so we kind of hung out. The show hadn't started," Greenberg said. As attendees moved to tables, they did too— then enjoyed a meal and the concert. "After the performance, Willie came out. He had a drink with us and took a picture with us. … It was a really fun time." Big leaps In a Dec. 10 ceremony in Sweden, James Allison and Tasuku Honjo will each receive a Nobel medal and diploma. The scientists will also share a $1 million prize. Allison is the first Nobel laureate for MD Anderson, where he is a professor and chair of the department of immunology. He is the executive director of the Immunotherapy Platform, which is part of MD Anderson's Moon Shots Program—an ambitious effort to more rapidly reduce cancer deaths and suffering by developing advances in prevention, early detection and treatment based on scientific discover- ies. In addition, Allison holds the Vivian L. Smith Distinguished Chair in Immunology and serves as deputy director of the David H. Koch Center for Applied Research of Genitourinary Cancers in the depart- ment of genitourinary medical oncology. "The miracles actually come out of deep science and understand- ing how it works," Allison explained, following a parade in his honor when he returned to MD Anderson a few days after winning the Nobel. "Our work on this molecule, CTLA-4, had nothing to do with cancer— it had to do with understanding how T cells work. And once we figured it out, then I was able to say: 'Oh, maybe we could do this' and take it to the clinic." After technology billionaire Sean Parker invested $250 million in 2016 to form the Parker Institute for Cancer Immunotherapy— a research collaboration between six leading academic research insti- tutions in the United States—Allison, Lanier and Ribas were selected to direct the Parker centers on their respective campuses. In mid-October, Allison was asked to offer advice to young sci- entists during an online chat hosted by STAT news. His thoughtful response articulated the philosophy of his steady, four-decade pursuit. "Follow your heart. Find something you're really interested in. Do absolutely the best you can at your science without a whole lot of regard for potential translation—that can come later," he wrote. "When you really understand something, then you can think about how it'll be applied. Don't start with trying to solve a particular issue of medicine; you're unlikely to find any great leaps or findings. The big leaps come from understanding fundamental mechanisms in detail." Follow your heart. Find something you're really interested in. Do absolutely the best you can at your science without a whole lot of regard for potential translation— that can come later. When you really understand something, then you can think about how it'll be applied. — JAMES ALLISON, PH.D.